Orexo develops improved specialty pharmaceuticals and treatments for new areas of use – at a lower cost, in a shorter period of time and at a lower risk – by combining known substances with patented proprietary technologies.
Zubsolv® is a product for the maintenance treatment of opioid dependence. On July 3, 2013, the product was approved by the U.S. Food and Drug Administration, FDA and on September 16, 2013, the product was launched on the US market.
Abstral® is a product that provides rapid relief of breakthrough pain in cancer patients. In March 2013, Orexo sold the rights to Abstral in the United States to Galena Biopharma, Inc. Orexo’s Japanese partner Kyowa Hakko Kirin Co., Ltd. holds the rights for Abstral in Japan. In September 2013, Abstral was approved in Japan. ProStrakan Group plc acquired the product rights in the EU and the rest of the world.
Edluar® is a product for the treatment of short-term insomnia. The specialty pharma company Meda has a global license for Edluar.
Orexo also markets Diabact® UBT, Heliprobe® System and IRIS™ through its subsidiary Kibion. These are used in the diagnosis of Helicobacter pylori, the bacterium that causes gastric ulcers.
OX51, prevention of acute pain during diagnostic and therapeutic procedures. OX51 is a novel sublingual formulation comprising alfentanil. The project has beeen developed to meet the rapidly growing demand for effective pain relief during short-term surgical and invasive diagnostic procedures.
OX-PMI, PGE2-inhibition, treatment of inflammatoric pain. The aim with this project is to develop a completely new class of products based on Orexo's prostaglandin research. In August 2014, Orexo's partner Boehringer Ingelheim decided to return the OX-MPI (selective inhibition of prostaglandin E2 synthase) to Orexo. Boehringer Ingelheim had been responsible for all research and development within the OX-MPI project since 2005. Orexo still sees potential in the project due to a unique target, an identified development compound and several granted patents.